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  • Title: [3 years' experience of radiation therapy with fast neutrons on the V-120 cyclotron].
    Author: Zyrianov BN, Musabaeva LI, Lisin VA, Lavrenkov KA, Kitsmaniuk ZD.
    Journal: Vopr Onkol; 1989; 35(11):1341-5. PubMed ID: 2609526.
    Abstract:
    The paper discusses the results of treatment of 128 patients with head and neck cancer in whom fast neutrons (Y-120; approximately 6.2 MeV) were used as a single procedure or in combination with surgery. Tumors of different histomorphologic structure displayed unequal sensitivity to fast neutrons. Mean disease-free survival in patients with complete regression of tumor was 24 months following neutron therapy alone, 18.5 months after combined neutron-photon treatment and 5.5 months only in controls. Relapse rates were 20 and 15% in patients with pre- and postoperative neutron treatment, respectively, as compared to 52% in controls.
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