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  • Title: [Liver morphology in delta virus hepatitis].
    Author: Loginov AS, Aruin LI, Shatalova OL, Krenchyk D, Ponomarenko AM.
    Journal: Arkh Patol; 1989; 51(10):18-25. PubMed ID: 2610600.
    Abstract:
    Biopsy material from two groups of patients with liver diseases is studied. 12 patients with a high titer of total anti-delta (D)-antibodies are included into the 1st group. In this group, among patients with total antibodies to D-infection D-antigen in the liver tissue is found in 6 cases with a pronounced chronic aggressive hepatitis (CAH) and active liver cirrhosis (ALC). The 2nd group consisted of 30 patients with CAH and ALC and D-antigen was observed in 10 cases. Hepatocyte degeneration and pronounced lobular infiltration were the only distinctive feature of liver morphology in D-positive cases as compared to the D-negative ones. The presence of D-antigen always correlated with an active inflammatory process.
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