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  • Title: [Aggregation of isolated myofibrils stimulated by their contraction. II. Aggregation mechanism].
    Author: Shelud'ko NS, Korchagin VP, Kropacheva IV, Iudin IuK.
    Journal: Biofizika; 1989; 34(5):840-3. PubMed ID: 2611283.
    Abstract:
    Aggregation of contracted myofibrils was studied as a function of experimental conditions at myofibril contraction. The aggregation rate increased at higher concentrations of suspensions and at increased ionic strength of the medium to achieve the maximum at 0.1 M KCL in the last case. The aggregate sizes grow with an increase of ionic strength and concentration of MgATP and reduce with addition of F-actin. Aggregation of myofibrils develops only in the case of their complete or significant contraction. It was suggested that aggregation is stimulated by dehydration of myofibril at contraction.
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