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  • Title: Owl monkey gene map: evidence for a homologous human chromosome 7q region near the cystic fibrosis locus.
    Author: Ma NS, Harris TS, Watkins P, Tsui LC.
    Journal: Genomics; 1989 Oct; 5(3):389-96. PubMed ID: 2613227.
    Abstract:
    We have demonstrated the assignments of two gene loci (COLIA2, MET) and two noncoding DNA markers (D7S13, D7S8) to owl monkey chromosome 14 (K-VI) by hybridizing DNA probes from the cystic fibrosis (CF) region of human chromosome 7q21-32 to panels of rodent-owl monkey somatic cell hybrids. The assignments are substantiated by in situ chromosome hybridization of markers COLIA2, MET, and D7S13 to the distal long arm of chromosome 14 (K-VI). These results support genomic conservation of the human CF region, at least in the higher primates.
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