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  • Title: Flavovirin--a new antifungal antibiotic produced by the pyrenomycete Melanconis flavovirens.
    Author: Sailer M, Sasek V, Sejbal J, Budĕsínký M, Musílek V.
    Journal: J Basic Microbiol; 1989; 29(6):375-81. PubMed ID: 2614675.
    Abstract:
    The pyrenomycete Melanconis flavovirens was found to produce a mixture of two antifungal antibiotics. The first has been already described; the antibiotic is identical with thermozymocidin (myriocin). The second antibiotic is a new compound, whose isolation and identification is presented in this paper. The chemical structure of this substance (C21H37NO5) was determined to be 2-amino-2-hydroxymethyl-3,4-trans-epoxy-14-oxo-eicos-trans-6-enoic acid. After the producer it was named flavovirin and it possesses strong activity against yeasts and a moderate effectivity against filamentous fungi.
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