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Title: Synthesis of self-reporting polymeric nanoparticles for in situ monitoring of endocytic microenvironmental pH. Author: Qiao ZY, Hou CY, Zhao WJ, Zhang D, Yang PP, Wang L, Wang H. Journal: Chem Commun (Camb); 2015 Aug 14; 51(63):12609-12. PubMed ID: 26156029. Abstract: The bis(pyrene) conjugated pH-sensitive polymers () were synthesized and self-assembled into nanoparticles through hydrophobic interactions. The Nile red (NR) loaded nanoparticles showed red emission due to the FRET effect. The nanoparticles entered cells via endocytosis, and the microenvironmental pH in the endocytosis process was monitored in situ by the simultaneous dual-wavelength fluorescence changes.[Abstract] [Full Text] [Related] [New Search]