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  • Title: Pachydermoperiostosis and bladder cancer.
    Author: Famularo G, Stasolla A, Gasbarrone L.
    Journal: Dermatol Online J; 2015 Jun 16; 21(6):. PubMed ID: 26158372.
    Abstract:
    Pachydermoperiostosis or the Touraine-Soulente-Golé syndrome is a rare monogenetic disorder characterized by pachydermia, periostosis and digital clubbing accounts for approximately 3∼5% of all patients with hypertrophic osteoarthropathy. Missense mutations in SLCO2A1 and HPGD genes could plausibly underlie the pathogenesis of pachydermoperiostosis. Patients have usually a favorable outcome with very few cases associated with cancer. Herein, we report the first case of a patient with pachydermoperiostosis associated with bladder cancer.
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