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  • Title: Efficient Synthesis of 3,3'-Mixed Bisindoles via Lewis Acid Catalyzed Reaction of Spiro-epoxyoxindoles and Indoles.
    Author: Hajra S, Maity S, Maity R.
    Journal: Org Lett; 2015 Jul 17; 17(14):3430-3. PubMed ID: 26158390.
    Abstract:
    An efficient strategy for the synthesis of 3-(3-indolyl)-oxindole-3-methanol has been developed to achieve a Lewis acid catalyzed, highly regioselective ring opening of spiro-epoxyoxindoles with indoles. The method is used for the gram-scale formal total synthesis of (±)-gliocladin C.
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