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  • Title: [Progressive systemic sclerosis, B-cell malignant lymphoma of the ileum and thyroid adenocarcinoma].
    Author: Rodrigues CJ, Bisi H, Yoshinari N, Marchiori PE, Cossermelli W.
    Journal: Rev Hosp Clin Fac Med Sao Paulo; 1989; 44(2):84-6. PubMed ID: 2616991.
    Abstract:
    A patient with progressive systemic sclerosis with rapid evolution to death is presented. The post-morten examination revealed besides the typical changes of the progressive systemic sclerosis in the skin, kidneys, heart and blood vessels a B-cell ileal malignant lymphoma with generalized metastases, and an adenocarcinoma of the thyroid gland. A possible mechanism involved in the association of these diseases might be the action of the oncogenes modifying the cellular hormostasis and the immunological tolerance.
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