MEDLINE/PubMed Journal Browser Search

Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

Title: [Study on the Relationship between the Inhalable Fine Particulate Matter of Xuanwei Coal Combustion and Lung Cancer].
Author: Yang J, Cao Y, Huang Y, Li G, Ye L, Zhao G, Lei Y, Chen X, Tian L.
Journal: Zhongguo Fei Ai Za Zhi; 2015 Jul; 18(7):403-8. PubMed ID: 26182864.
Abstract:
BACKGROUND AND OBJECTIVE: The high incidence of lung cancer in Xuanwei, China, has become an important restricting factor for livelihood development, thus exerting local social and economic impacts. Coal is the main fuel of the local community and also the main source of indoor pollution. This study aims to explore the coal combustion inhalable fine particulate matter (PM2.5) and its component output differences in different areas of Xuanwei, Yunnan. Moreover, the aim of this study is to investigate the relationship between inhalation of fine particles and high incidence of local lung cancer. METHODS: For combustion test, coal mines designated as C1, K7 and M30 were collected from LaoLin Colliery of Laibing Town, Huchang Colliery of Baoshan Town, and Taiping Colliery of Wenxing Town in Xuanwei, respectively. PM2.5 of indoor air was weighed, analyzed for elemental composition, and morphologically compared. The pathological specimen of lung cancer patients in Xuanwei who underwent operation was observed through electron microscope. RESULTS: The PM2.5 concentrations in indoor air were (8.244 ±1.460) mg/m³ (C1), (5.066±0.984) mg/m³ (K7), and (5.071±1.460) mg/m³ (M30). The differences among pairwise comparisons were statistically significant (P=0.029). The filter impurities of C1 coal seam primarily include Si- and O-enriched compounds. Moreover, three membranes that comprised other elements, including C, S, and Si, were observed. These membranes were evident from the aggregation of silica and a Ca-Al membrane. Compared with that of other coal seams, C1 coal generated a mass of impurities, in which several particles have irregular shape. We found nanoscale fine particles in some specimens of Xuanwei lung cancer patients. CONCLUSIONS: The produced combustion of C1 coal was different from that of K7 and M30 coal. PM2.5 composition may be associated with the high local incidence of lung cancer. . 背景与目的云南省宣威地区是中国乃至世界肺癌的高发区，肺癌已成为制约当地社会经济发展和影响社会民生的重要因素。煤炭是当地主要的生活燃料，燃煤是当地室内污染的主要来源。本研究探讨云南宣威不同肺癌发病率地区烟煤燃烧过程中可吸入细颗粒物（fine particulate matter, PM2.5）产出情况，以及不同地区PM2.5成分异同。探讨吸入细颗粒物与当地肺癌高发的关系。方法收集宣威市来宾镇老林煤矿C1煤层、宝山镇虎场煤矿K7煤层、文兴镇太平煤矿M30煤层的煤矿进行燃烧试验。收集室内的空气中的PM2.5进行称重，元素分析，用电子显微镜观察其形态，对比三种PM2.5异同。对宣威地区的肺癌患者的术后标本进行电子显微镜观察。结果室内空气中的PM2.5浓度分别为C1煤（8.244±1.460）mg/m³，K7煤（5.066±0.984）mg/m³，K7煤（5.071±1.460）mg/m³；三组空气中PM2.5浓度两两比较差异有统计学意义（Ρ=0.029）。C1煤层中滤膜上的杂质有（Silicon, Si）和氧（Oxygen, O）元素富集，三组滤膜上均发现了碳（Carbon, C），硫（Sulfur, S）的聚集，在部分的滤膜上可见游离的二氧化硅（SiO2），部分滤膜上有铝（Aluminium, Al）、钙（Calcium, Ca）元素的聚集。C1煤层与其他煤层相比所产生颗粒物形态不规则，成团块状，杂质较多。在部分的宣威来宾地区的肺癌患者术后标本中，发现纳米级细颗粒的杂质。结论 C1煤与K7和M30煤燃烧产生的PM2.5不同，PM2.5的成分可能与当地肺癌高发相关。. 背景与目的云南省宣威地区是中国乃至世界肺癌的高发区，肺癌已成为制约当地社会经济发展和影响社会民生的重要因素。煤炭是当地主要的生活燃料，燃煤是当地室内污染的主要来源。本研究探讨云南宣威不同肺癌发病率地区烟煤燃烧过程中可吸入细颗粒物（fine particulate matter, PM2.5）产出情况，以及不同地区PM2.5成分异同。探讨吸入细颗粒物与当地肺癌高发的关系。方法收集宣威市来宾镇老林煤矿C1煤层、宝山镇虎场煤矿K7煤层、文兴镇太平煤矿M30煤层的煤矿进行燃烧试验。收集室内的空气中的PM2.5进行称重，元素分析，用电子显微镜观察其形态，对比三种PM2.5异同。对宣威地区的肺癌患者的术后标本进行电子显微镜观察。结果室内空气中的PM2.5浓度分别为C1煤（8.244±1.460）mg/m³，K7煤（5.066±0.984）mg/m³，K7煤（5.071±1.460）mg/m³；三组空气中PM2.5浓度两两比较差异有统计学意义（Ρ=0.029）。C1煤层中滤膜上的杂质有（Silicon, Si）和氧（Oxygen, O）元素富集，三组滤膜上均发现了碳（Carbon, C），硫（Sulfur, S）的聚集，在部分的滤膜上可见游离的二氧化硅（SiO2），部分滤膜上有铝（Aluminium, Al）、钙（Calcium, Ca）元素的聚集。C1煤层与其他煤层相比所产生颗粒物形态不规则，成团块状，杂质较多。在部分的宣威来宾地区的肺癌患者术后标本中，发现纳米级细颗粒的杂质。结论 C1煤与K7和M30煤燃烧产生的PM2.5不同，PM2.5的成分可能与当地肺癌高发相关。.

[Abstract] [Full Text] [Related] [New Search]