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  • Title: Placental proteins 12 and 14 in pre-eclampsia.
    Author: Howell RJ, Economides D, Teisner B, Farkas AG, Chard T.
    Journal: Acta Obstet Gynecol Scand; 1989; 68(3):237-40. PubMed ID: 2618607.
    Abstract:
    The concentrations of circulating placental protein 12 (PP12) and placental protein 14 (PP14) were measured in 41 patients with pre-eclampsia and in 17 control subjects. The levels of PP12 were significantly elevated in patients with severe preeclampsia, whereas PP14 levels were unaffected. There was a negative correlation between the levels of both PP12 and PP14 and birthweight. PP12 and PP14 appear therefore to have different control mechanisms and, possibly, different cellular origins within the decidua.
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