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  • Title: Correction of the abnormal ratio of OKT4+ to OKT8+ peripheral blood lymphocytes in patients suffering from juvenile arthritis (JCA) by the extract from calf thymuses.
    Author: Podwysocka M, Wieczorek Z, Zimecki M, Prusek W, Wieczorek E, Spiegel K.
    Journal: Arch Immunol Ther Exp (Warsz); 1989; 37(1-2):127-32. PubMed ID: 2619496.
    Abstract:
    Children suffering from JCA showed an elevated percentage of OKT4+ T lymphocytes and an increased ratio of OKT4+ to OKT8+ lymphocytes. Several children showing a significant aggravation of the disease, were selected for a 3-week treatment with TFX. In 7 out of 10 patients a pronounced clinical and laboratory improvement was registered, accompanied by a normalization of the OKT4+ to OKT8+ lymphocyte ratio.
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