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  • Title: A fluorescent G-quadruplex probe for the assay of base excision repair enzyme activity.
    Author: Lee CY, Park KS, Park HG.
    Journal: Chem Commun (Camb); 2015 Sep 18; 51(72):13744-7. PubMed ID: 26214499.
    Abstract:
    A sensitive and selective assay of uracil DNA glycosylase (UDG) activity is developed by utilizing a G-quadruplex probe incorporating 2-aminopurine (2-AP), based on a novel design that excision reaction promoted by UDG triggers the formation of G-quadruplex structure with significant fluorescence enhancement of 2-AP within the probe.
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