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Title: Structure of GTP-specific succinyl-CoA synthetase in complex with CoA. Author: Huang J, Malhi M, Deneke J, Fraser ME. Journal: Acta Crystallogr F Struct Biol Commun; 2015 Aug; 71(Pt 8):1067-71. PubMed ID: 26249701. Abstract: Pig GTP-specific succinyl-CoA synthetase is an αβ-heterodimer. The crystal structure of the complex with the substrate CoA was determined at 2.1 Å resolution. The structure shows CoA bound to the amino-terminal domain of the α-subunit, with the free thiol extending from the adenine portion into the site where the catalytic histidine residue resides.[Abstract] [Full Text] [Related] [New Search]