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  • Title: [Benzonitrile and derivatives. Synthesis and pharmacological study of alkyl para-cyanophenoxy alkanoates on the central nervous system].
    Author: Kirkiacharian S, Goma JR, Cheav SL, Bretaudeau J, Foussard-Blanpin O.
    Journal: Ann Pharm Fr; 1989; 47(1):16-23. PubMed ID: 2627099.
    Abstract:
    The results obtained by the pharmacological study of alkyl para-cyanophenoxy alkanoates seem to indicate that these derivatives present a sedative effect on the central nervous system. This activity increases with the number of methyl groups substituted, on ethyl para-cyanophenoxy acetate (except the motricity composent), most probably because of an increase in lipophily and therefore in the fixation on the central nervous system.
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