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  • Title: [Effect of phentolamine on the reflex increase in arterial pressure].
    Author: Orani GP, Decandia M.
    Journal: Boll Soc Ital Biol Sper; 1989 Dec; 65(12):1119-25. PubMed ID: 2627326.
    Abstract:
    Experiments were carried out in anaesthetized and curarized cats to study the effects of the alpha-blocker phentolamine on arterial pressor response to stimulation of group I afferent fibers from gastrocnemius-soleus muscles. It has been found that increasing doses of phentolamine given i.v. cause a decreasing pressor response until complete disappearance occurs at 2.5 mg/Kg. It is concluded that pressor response is present only when the adrenergic control system is effective and, therefore, it is due mainly to an increase in peripheral vascular resistances.
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