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  • Title: [The evaluation of nonspecific bronchial hyperreactivity in diseases with an asthmatic reaction].
    Author: Hamzagić H, Ustamujić A, Pazin R.
    Journal: Med Arh; 1989; 43(2-3):113-6. PubMed ID: 2628662.
    Abstract:
    The quantitative acetylcholine testing has been done at 62 patients, 45 suffering of bronchial asthma, 8 with intrinsic one, and 9 with bronchitis asthmatiformis. According to the groups of diseases, the effective changes of acetylcholine threshold doses of single concentrations which produced the bronchial hyperreactivity, were registered and compared with cumulative doses of all previous concentrations with no effect. Statistical analysis showed that threshold dose which can produce bronchial hyperreactivity, is individual and it is not caused by the kind of disease with bronchospastic reaction. Also, it was proved that the eventual effect of cumulative doses, during the provocation with more acetylcholine concentrations, and with 10 or 15 minutes pause, has no significance for acetylcholine testing quality.
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