These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Label-free detection of Cu(II) in a human serum sample by using a prion protein-immobilized FET sensor.
    Author: Wustoni S, Hideshima S, Kuroiwa S, Nakanishi T, Mori Y, Osaka T.
    Journal: Analyst; 2015 Oct 07; 140(19):6485-8. PubMed ID: 26288852.
    Abstract:
    We have developed a field effect transistor (FET) sensor to sensitively detect copper ions (Cu(2+)) in a human serum (HS) sample for promising health-care diagnosis. By utilizing a Cu(2+)-binding prion protein that was immobilized on the FET gate surface, such an FET sensor can provide a simple, label free and highly selective performance, even in HS samples. We demonstrated the sensitivity of the sensor at the nanomolar level, 0-100 nM, which is very useful for the detection range of Cu(2+) deficiency in practical applications.
    [Abstract] [Full Text] [Related] [New Search]