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  • Title: Silver(I)-Catalyzed Dearomatization of Alkyne-Tethered Indoles: Divergent Synthesis of Spirocyclic Indolenines and Carbazoles.
    Author: James MJ, Clubley RE, Palate KY, Procter TJ, Wyton AC, O'Brien P, Taylor RJ, Unsworth WP.
    Journal: Org Lett; 2015 Sep 04; 17(17):4372-5. PubMed ID: 26293968.
    Abstract:
    A high-yielding, divergent approach to generate either spirocyclic indolenines or carbazoles from a common indole-tethered propargyl alcohol precursor is described, with mechanistic insight provided. Either product can be obtained upon treatment with different Ag(I) catalysts at rt. An unexpected hydration reaction to afford (±)-actinopolymorphol B is also reported.
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