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  • Title: Near-infrared spectroscopic photoacoustic microscopy using a multi-color fiber laser source.
    Author: Buma T, Wilkinson BC, Sheehan TC.
    Journal: Biomed Opt Express; 2015 Aug 01; 6(8):2819-29. PubMed ID: 26309746.
    Abstract:
    We demonstrate a simple multi-wavelength optical source suitable for spectroscopic optical resolution photoacoustic microscopy (OR-PAM) of lipid-rich tissue. 1064 nm laser pulses are converted to multiple wavelengths beyond 1300 nm via nonlinear optical propagation in a birefringent optical fiber. OR-PAM experiments with lipid phantoms clearly show the expected absorption peak near 1210 nm. We believe this simple multi-color technique is a promising cost-effective approach to spectroscopic OR-PAM of lipid-rich tissue.
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