These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Chiral cyclopentadienyl iridium(III) complexes promote enantioselective cycloisomerizations giving fused cyclopropanes.
    Author: Dieckmann M, Jang YS, Cramer N.
    Journal: Angew Chem Int Ed Engl; 2015 Oct 05; 54(41):12149-52. PubMed ID: 26310394.
    Abstract:
    The cyclopentadienyl (Cp) group is a very important ligand for many transition-metal complexes which have been applied in catalysis. The availability of chiral cyclopentadienyl ligands (Cp(x) ) lags behind other ligand classes, thus hampering the investigation of enantioselective processes. We report a library of chiral Cp(x) Ir(III) complexes equipped with an atropchiral Cp scaffold. A robust complexation procedure reliably provides Cp(x) Ir(III) complexes with tunable counterions. In a proof-of-concept application, the iodide-bearing members are shown to be highly selective for enyne cycloisomerization reactions. The dehydropiperidine-fused cyclopropane products are formed in good yields and enantioselectivities.
    [Abstract] [Full Text] [Related] [New Search]