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  • Title: Synthesis and herbicidal activities of benzothiazole N,O-acetals.
    Author: Ji Z, Zhou F, Wei S.
    Journal: Bioorg Med Chem Lett; 2015 Oct 01; 25(19):4065-8. PubMed ID: 26318996.
    Abstract:
    A new series of N,O-acetals were prepared via a simple one-pot reaction by the condensation of 2-amino-methybenzothiazole with aldehydes and alcohols. The title compounds were obtained in moderate to good yields in the presence of acid catalyst. Bioassay results indicated that some synthesized compounds had good herbicidal activity against both dicotyledon and monocotyledon weeds. This investigation provided a new type of herbicidal lead compounds, as well as its facile preparation method.
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