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  • Title: [Epidermoid carcinoma of the esophagus: preliminary results of combined treatment].
    Author: Merlini M, Gabellon S, Elbaze W, Genton A, Leyvraz S, Chapuis G, Savary M.
    Journal: Helv Chir Acta; 1989 Dec; 56(4):431-4. PubMed ID: 2632466.
    Abstract:
    In 1986, a prospective study was started in CHUV on the squamous-cell carcinoma of the esophagus treated with a multimodality protocol associating preoperative chemotherapy and surgery. Nineteen patients are currently followed-up. Dysphagia is the main symptom and was found in 16 patients (84%). After chemotherapy, dysphagia disappeared completely in 7 cases (44%), regressed in 7 other cases and worsened in 1 case. Twelve patients were operated on, without operative mortality. Histologically, no tumor was found in one case (5%) after the preoperative treatment. Follow-up is currently too short to draw statistical conclusions. The rationale, advantages and perspectives of the multimodality treatment are presented and compared with different recent series.
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