These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Cloning and structural analysis of genes coding for tumor necrosis factor and lymphotoxin in rabbits].
    Author: Shakhov AN, Kuprash DV, Turetskaia RL, Azizov MM, Andreeva AV, Nedospasov SA.
    Journal: Mol Biol (Mosk); 1989; 23(6):1743-50. PubMed ID: 2633043.
    Abstract:
    Genes, coding for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta), have been cloned from the rabbit genomic library. The two genes are tandemly arranged and separated only by 1 kb of DNA as previously observed in human and mouse genomes. We have sequenced the entire rabbit lymphotoxin gene (LT) and calculated the amino acid sequence of the rabbit LT whose cDNA is not yet cloned. We also analyzed the upstream sequences of this gene and revealed a number of recognition sites for the known transcriptional factors. The rabbit TNF gene comprised in the cloned genomic region has been sequenced earlier.
    [Abstract] [Full Text] [Related] [New Search]