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  • Title: [Magnetic resonance imaging of bladder tumors: superiority of serial "Fast SE" assisted by Gd-DTPA in tumor staging].
    Author: Tanimoto A, Yuasa Y, Endo M, Ohkawa S, Shiraga N, Fujisawa H, Ido K, Ogawa K, Momoshima S, Shiga H.
    Journal: Nihon Igaku Hoshasen Gakkai Zasshi; 1989 Dec 25; 49(12):1552-66. PubMed ID: 2633133.
    Abstract:
    Eighteen cases with bladder tumors were examined by means of superconducting MRI. Sequences used were spin echo (TR/TE (msec) = 500/20 as T1WI (weighted image) and 1500/80 as T2WI) and serial "fast spin echo (fast SE)" pre/post Gd-DTPA administration. "Fast SE" was a new technique offering a distinct T1WI (TR/TE = 100/14, utilizing a 14 second breath hold). Slice thickness of "fast SE" was 10 mm and slice plane was selected perpendicular to the tumor base to detect the extent of invasion. Serial scan of "fast SE" was performed before and immediately after 0.1 mmol/kg Gd administration. Scanning was completed before the bladder was opacified by Gd. Tumor and normal mucosa were both markedly enhanced whereas the surrounding muscle layer remained hypointense. On delayed scan, the elevated character of the tumor was outlined by opacified urine but the distinction between the mucosa and the muscle layer became unclear. Total cystectomy (TC) was performed in 6 of 18 cases and pathological tumor extension was correlated with MR findings. Transurethral resection (TUR) was performed in the remaining 12 patients, and the tumor extension was assessed by follow-up biopsy after TUR. Intact liner hypointensity indicated superficial lesions (= less than pT2), while disruption of the linear hypointensity corresponded pathologically to deep muscle invasion (= greater than pT3a). Accuracy of serial "fast SE" in tumor staging was 94% (17/18). Serial "fast SE" allowed the distinction of superficial from invasive tumors more accurately than conventional studies, and therefore assisted in choosing the correct operative method.
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