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  • Title: Effect of herbicide banvel on rabbit vaginal mucus membrane.
    Author: Agnihotri PK, Murthy PS, Mukherjee SK.
    Journal: Indian J Exp Biol; 1989 Dec; 27(12):1090-1. PubMed ID: 2633971.
    Abstract:
    Effect of banvel and its active ingredient, dicamba (3,6-dichloro-o-anisic acid) was investigated employing rabbit mucus membrane irritancy test. Inflammatory changes which did not exceed an average score of 2+ were observed in the animals 48 hr after a single intravaginal application of banvel (0.1 ml/rabbit) and dicamba (100 mg/rabbit). Persistent histopathological changes were observed in 1 out of 6 banvel-treated rabbits 15 days post-application. The results suggest that banvel and dicamba are not primary irritants but should nevertheless be employed with caution.
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