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Title: Polyoxygenated cyclohexene derivatives isolated from Dasymaschalon sootepense and their biological activities. Author: Hongthong S, Kuhakarn C, Jaipetch T, Prabpai S, Kongsaeree P, Piyachaturawat P, Jariyawat S, Suksen K, Limthongkul J, Panthong A, Nuntasaen N, Reutrakul V. Journal: Fitoterapia; 2015 Oct; 106():158-66. PubMed ID: 26347951. Abstract: Six new naturally occurring polyoxygenated cyclohexene derivatives together with eight related known derivatives, two known alkaloids, and two known flavonoid derivatives were isolated from bioassay-guided fractionation of the ethyl acetate extract of the leaves and twigs of Dasymaschalon sootepense. The structure elucidation and determination of absolute configurations were established by various spectroscopic methods, X-ray diffraction techniques as well as comparison with the literature data. Several isolated compounds were evaluated for their cytotoxic, anti-HIV-1 RT and anti-inflammatory activities.[Abstract] [Full Text] [Related] [New Search]