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  • Title: [Clinical value of serum copper, zinc and copper/zinc ratio in the differentiation of sarcoidosis from pulmonary tuberculosis and pulmonary carcinoma].
    Author: Hua B.
    Journal: Zhonghua Jie He He Hu Xi Za Zhi; 1989 Aug; 12(4):212-3, 253-4. PubMed ID: 2636945.
    Abstract:
    Serum Cu, SZn and SCu/Zn ratio were studied in 14 patients with sarcoidosis, 72 patients with pulmonary tuberculosis, 15 patients with pulmonary carcinoma and 50 healthy persons as control. The results were: no significant differences were found between control group and sarcoidosis group in SCu, SZn and SCu/Zn ratio. In tuberculosis group and carcinoma group SCu increased and SZn decreased. Therefore, the SCu/Zn ratio increased significantly. The results suggested that SCu less than 1.2 ppm (means + 2 s), SZn greater than 0.8 ppm (means - 2 s) and SCu/Zn ratio less than 1.5 were helpful for the differential diagnosis of sarcoidosis from pulmonary tuberculosis and pulmonary carcinoma.
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