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  • Title: [Eosinophilic pleuritic: An unusual complication of treatment with an angiotensin converting enzyme inhibitor].
    Author: Zouak A, Bongrain É, Launois C, Nardi J, Vella-Boucaud J, Deslee G, Lebargy F, Perotin JM.
    Journal: Rev Mal Respir; 2015 Sep; 32(7):737-41. PubMed ID: 26370487.
    Abstract:
    BACKGROUND: Eosinophilic pleural effusions are defined by an eosinophil count ≥10% in pleural fluid and represent approximately 10% of exudative pleural effusions. OBSERVATION: We report the first case of eosinophilic pleural effusion occurring due to lisinopril treatment. Improvement after drug discontinuation and recurrence after reintroduction indicated that lisinopril was responsible for the effusion. CONCLUSION: The main causes of eosinophilic pleural effusions are infections including tuberculosis, and malignancies. Drug-induced eosinophilic pleural effusions have only rarely been described, mainly caused by cardiovascular or neuropsychiatric medicines.
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