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Title: Can chest high-resolution computed tomography findings diagnose pulmonary alveolar microlithiasis? Author: Francisco FA, Rodrigues RS, Barreto MM, Escuissato DL, Araujo Neto CA, Silva JL, Silva CS, Hochhegger B, Souza AS, Zanetti G, Marchiori E. Journal: Radiol Bras; 2015; 48(4):205-10. PubMed ID: 26379317. Abstract: OBJECTIVE: The present study was aimed at retrospectively reviewing high-resolution computed tomography (HRCT) findings in patients with pulmonary alveolar microlithiasis in order to evaluate the frequency of tomographic findings and their distribution in the lung parenchyma. MATERIALS AND METHODS: Thirteen patients (9 females and 4 males; age, 9 to 59 years; mean age, 34.5 years) were included in the present study. The HRCT images were independently evaluated by two observers whose decisions were made by consensus. The inclusion criterion was the presence of abnormalities typical of pulmonary alveolar microlithiasis at HRCT, which precludes lung biopsy. However, in 6 cases lung biopsy was performed. RESULTS: Ground-glass opacities and small parenchymal nodules were the predominant tomographic findings, present in 100% of cases, followed by small subpleural nodules (92.3%), subpleural cysts (84.6%), subpleural linear calcifications (69.2%), crazy-paving pattern (69.2%), fissure nodularity (53.8%), calcification along interlobular septa (46.2%) and dense consolidation (46.2%). CONCLUSION: As regards distribution of the lesions, there was preferential involvement of the lower third of the lungs. No predominance of distribution in axial and anteroposterior directions was observed. OBJETIVO: Analisar, retrospectivamente, as tomografias computadorizadas de alta resolução (TCAR) de pacientes com microlitíase alveolar pulmonar, a fim de avaliar a frequência dos padrões tomográficos e sua distribuição no parênquima pulmonar. MATERIAIS E MÉTODOS: O estudo incluiu 13 pacientes (9 femininos e 4 masculinos) com idades variando de 9 a 59 anos (média de 34,5 anos). Os exames foram avaliados por dois observadores, de modo independente, e os casos discordantes, resolvidos por consenso. O critério de inclusão foi a presença de anormalidades na TCAR típicas de microlitíase alveolar pulmonar, o que prescinde a necessidade de exame histopatológico. Entretanto, em 6 casos foram realizadas biópsias pulmonares. RESULTADOS: Os achados tomográficos predominantes foram opacidades em vidro fosco e pequenos nódulos parenquimatosos, presentes em 100% dos casos, seguidos de pequenos nódulos subpleurais (92,3%), cistos subpleurais (84,6%), calcificações lineares subpleurais (69,2%), padrão de pavimentação em mosaico (69,2%), fissura nodular (53,8%), calcificação ao longo dos septos interlobulares (46,2%) e consolidações densas (46,2%). CONCLUSÃO: Quanto à distribuição dos achados, houve acometimento preferencial dos terços inferiores. Não foi observado predomínio de distribuição dos sentidos axial e anteroposterior.[Abstract] [Full Text] [Related] [New Search]