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  • Title: [Changes in the TMJ in the intrauterine and extrauterine period of life].
    Author: Caltabiano M, Carnazza-Marraro ML, Caltabiano C, Martinez G, Leonardi R.
    Journal: Mondo Ortod; 1989; 14(3):291-300. PubMed ID: 2639231.
    Abstract:
    The aim of this work is the study of hte prenatal and postnatal development of the human temporomandibular joint. Ten of human embryos and fetuses and six joint of young children were sectioned sagittally and frontally, decalcified where necessary and stained using Mallory and Cajall-Callengo techniques. At the eighteen gestational week the condylar blastema became evident, the temporal blastema appeared later. At the twenty-second week all the structure of the joint were present, but the morphogenesis was not completed as one could observe from the preparations the Meckel's cartilage. A key observation from the study of features and embryos was that the condylar cartilage wasn't uniformly distributed on the condylar surface bur it was located in posterior-lateral area. At birth TMJ showed some characteristics typical of this period such as : a flat temporal component a disc with blood vessels and a condyle with connective-vascular channels. These characteristics will disappear later in the life at about 3-5 years.
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