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Title: A ratiometric chemodosimeter for highly selective naked-eye and fluorogenic detection of cyanide. Author: Lin WC, Hu JW, Chen KY. Journal: Anal Chim Acta; 2015 Sep 17; 893():91-100. PubMed ID: 26398427. Abstract: A simple indole-based chemosensor (1) with a very low molecular weight of 207 g mol(-1) has been synthesized for the highly reactive and selective detection of CN(-) in aqueous media, even in the presence of other anions, such as F(-), Cl(-), Br(-), AcO(-), [Formula: see text] , SCN(-), [Formula: see text] , [Formula: see text] , [Formula: see text] , BzO(-), [Formula: see text] , and [Formula: see text] . The sensor achieves rapid detection of cyanide anion in 2 min, and the pseudo-first-order rate constant is estimated as 1.576 min(-1). The colorimetric and ratiometric fluorescent response of the sensor to CN(-) is attributable to the addition of CN(-) to the electron-deficient dicyanovinyl group of 1, which prevents intramolecular charge transfer. The sensing mechanism is supported by density functional theory and time-dependent density functional theory calculations. Moreover, sensor 1 exhibits both high accuracy in determining the concentration of CN(-) in real samples and 1-based test strips can conveniently detect CN(-) without any additional equipment. The detection limit of the sensor 1 (1.1 μM) for cyanide is lower than the maximum permissible level of CN(-) (1.9 μM) in drinking water.[Abstract] [Full Text] [Related] [New Search]