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  • Title: Unilateral topical cortical application of penicillin: electrographic aspects. A new complement to an old model.
    Author: Cukiert A, Baumel SW, Andrioli MS, Marino R.
    Journal: Stereotact Funct Neurosurg; 1989; 53(3):202-8. PubMed ID: 2640062.
    Abstract:
    In 7 cats 800 IU of penicillin were applied diffusely over one hemisphere on the exposed neocortex. After 40 min all animals showed bilateral and synchronous burst discharges with a higher amplitude at the hemisphere where the penicillin had been applied. These data fill a gap in the literature concerning feline generalized penicillin epilepsy, in which penicillin is applied bilaterally on the exposed neocortex.
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