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  • Title: Effectiveness of Oral Antiseptics on Tooth Biofilm: A Study in vivo.
    Author: Mouchrek Junior JC, Nunes LH, Arruda CS, Rizzi Cde C, Mouchrek AQ, Tavarez RR, Tonetto MR, Bandeca MC, Maia Filho EM.
    Journal: J Contemp Dent Pract; 2015 Aug 01; 16(8):674-8. PubMed ID: 26423504.
    Abstract:
    AIM: To evaluate the effectiveness of five different mouthwashes through measurement of the plaque index. MATERIALS AND METHODS: Fifty subjects took part in this blind study, randomized into blocks of five groups according to the active ingredient of the mouthwash: CHX group (0.12% chlorhexidine gluconate), essential oils (EO) group, cetylpyridinium chloride (CPC) group, Tri group (triclosan) and Hamamelis virginiana (HV) group. All subjects were evaluated for a reduction in the bacterial plaque index at 7, 14 and 21 days. RESULTS: There was a significant reduction in the mean plaque index during the period of evaluation (p < 0.01), and the reduction during the period of evaluation was different between mouthwashes (p < 0.01). The reduction in the plaque index at the end of 21 days was, in decreasing order, CHX > EO > CPC > Tri > HV. CONCLUSION: The reduction in the plaque index during the period of evaluation was different between the types of mouth-wash. The mouthwash containing the active ingredient chlorhexidine was the most effective, followed by the essential oil, cetylpyridinium chloride, triclosan and H. virginiana.
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