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  • Title: Isolated Atrial Septal Defect Complicated by Tricuspid Valve Infective Endocarditis.
    Author: Shimbo M, Watanabe H, Abe T, Sato T, Koyama T, Yamamoto H, Ito H.
    Journal: Intern Med; 2015; 54(19):2463-5. PubMed ID: 26424304.
    Abstract:
    Infective endocarditis (IE) associated with atrial septal defect (ASD) is extremely rare. However, tricuspid regurgitation (TR) secondary to right ventricular overload is a potential cause of IE, and once it occurs, the development of a paradoxical embolism may lead to fatal complications. We herein report the case of a 50-year-old woman who was admitted due to a persistent fever resistant to antibiotics. Echocardiography showed secundum ASD, moderate TR and a mobile vegetation measuring 15×10 mm attached to the tricuspid valve. Given the risk of developing a paradoxical embolism, urgent surgery was successfully performed.
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