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  • Title: Nonpalpable breast tumors: diagnosis with stereotaxic localization and fine-needle aspiration.
    Author: Dowlatshahi K, Gent HJ, Schmidt R, Jokich PM, Bibbo M, Sprenger E.
    Journal: Radiology; 1989 Feb; 170(2):427-33. PubMed ID: 2643141.
    Abstract:
    Modern mammography is the most effective means of detecting nonpalpable breast cancers, but correct diagnosis for malignancy is made in only 20%-30% of the cases. The conventional method of lesion localization usually results in approximate placement of the hookwire in the breast. The authors report the results of stereotaxic localization, combined with fine-needle aspiration and cytologic study, performed in 528 cases. Clinically occult breast lesions were localized precisely (within 2 mm 96% of the time), sampled by means of a 23-gauge needle, and marked with either methylene blue or a hookwire for subsequent open excisional biopsy. The results indicate a sensitivity of 95%, specificity of 91%, and accuracy of 92% for the fine-needle aspiration procedure. This technique offers a significantly improved preoperative method of diagnosing small breast lesions with minimal pain, no complications, reduced cost, and no disfigurement or scar interfering with subsequent mammographic follow-up.
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