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Title: The Use of Interferons in the Treatment of Cutaneous T-Cell Lymphoma. Author: Spaccarelli N, Rook AH. Journal: Dermatol Clin; 2015 Oct; 33(4):731-45. PubMed ID: 26433845. Abstract: Interferons are polypeptides that naturally occur in the human body as a part of the innate immune response. By harnessing these immunomodulatory functions, synthetic interferons have shown efficacy in combating various diseases including cutaneous T-cell lymphoma. This article closely examines the qualities of interferon alfa and interferon gamma and the evidence behind their use in the 2 most common types of cutaneous T-cell lymphomas, namely, mycosis fungoides and Sézary syndrome.[Abstract] [Full Text] [Related] [New Search]