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  • Title: Isolation and Genome Characterization of the Virulent Staphylococcus aureus Bacteriophage SA97.
    Author: Chang Y, Shin H, Lee JH, Park CJ, Paik SY, Ryu S.
    Journal: Viruses; 2015 Oct 01; 7(10):5225-42. PubMed ID: 26437428.
    Abstract:
    A novel bacteriophage that infects S. aureus, SA97, was isolated and characterized. The phage SA97 belongs to the Siphoviridae family, and the cell wall teichoic acid (WTA) was found to be a host receptor of the phage SA97. Genome analysis revealed that SA97 contains 40,592 bp of DNA encoding 54 predicted open reading frames (ORFs), and none of these genes were related to virulence or drug resistance. Although a few genes associated with lysogen formation were detected in the phage SA97 genome, the phage SA97 produced neither lysogen nor transductant in S. aureus. These results suggest that the phage SA97 may be a promising candidate for controlling S. aureus.
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