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  • Title: [Effectiveness and safety of antiviral therapy of military personnel suffering from chronic hepatitis C].
    Author: Zhdanov KV, Gusev DA, Kozlov KV, Shishkin MK, Sukachev VS, Shakhmanov DM, Zhabrov SS.
    Journal: Voen Med Zh; 2015 Apr; 336(4):44-9. PubMed ID: 26454938.
    Abstract:
    In order to evaluate effectiveness and safety of antiviral therapy schemes examined and treated 191 patients with chronic bepatitis C were assigned standard interferon and ribavirin, pegslated interferon and ribavirin, the total duration of the course coput 24-48 weeks. Based on clinical and laboratory parameters evaluated the safety of antiviral therapy. Formation of sustainable viral response, depending on the genotype observed, was given at 58,9-70%.of patients. In case of insufficient. antiviral therapy was prescribed a second course that will improve the effectiveness of treatment to 90-95%. Correction of adverse events was held lower dosages of interferon and/or ribavirin.
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