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  • Title: EFFECT OF FLUORIDE VARNISHES CONTAINING DIFFERENT CALCIUM PHOSPHATE SOURCES ON MINERALIZATION OF INITIAL PRIMARY ENAMEL LESIONS.
    Author: Rirattanapong P, Vongsavan K, Saengsirinavin C, Pornmahala T.
    Journal: Southeast Asian J Trop Med Public Health; 2014 Nov; 45(6):1503-10. PubMed ID: 26466437.
    Abstract:
    This study was conducted to evaluate the effect of fluoride varnishes containing different calcium phosphate sources on demineralization of initial primary enamel lesions. Forty-eight sound primary incisors were completely coated with nail varnish except for two 1 x 1 mm windows before being placed in demineralizing solution for 4 days. After demineralization, one of the windows in each tooth was coated with nail varnish. The teeth were randomly divided into four groups (A to D; n = 12), and then the other (exposed) window was treated with: Group A: deionized water, Group B: Duraphat® fluoride varnish, Group C: Clinpro™ White varnish and Group D: Enamel Pro® varnish. The pH-cycling regimen was carried out consisting of demineralization (6 hours) and remineralization (18 hours) for 7 days. Polarized light microscopy was used to evaluate the lesion depth initially and then after a seven-day pH cycle. Lesion depth was measured using a computerized method with the Image-Pro® Plus Program. The pair t-test was used to compare lesion depths before and after treatment. Differences in mean lesion depths among the groups were compared with the one-way ANOVA and Tukey's multiple comparison tests with 95% confidence intervals. The lesion depths had a significant difference between before and after treatment of the all groups. There was a significant increase in lesion depth in Group A compared to the other groups. No significant differences were seen among Groups B, C and D, containing fluoride and the different calcium phosphate sources in inhibiting progression of initial primary enamel lesions.
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