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  • Title: POEMS syndrome associated with plasmacytoma of the clivus: "Time discovers the truth".
    Author: Thomas J, Maramattom BV, Varghese J, Kuruvilla PM.
    Journal: J Postgrad Med; 2016; 62(3):205-7. PubMed ID: 26469713.
    Abstract:
    Polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes (POEMS) syndrome is characterized by the presence of a monoclonal plasma cell disorder, peripheral neuropathy, and one or more of the following features: Osteosclerotic myeloma, Castleman's disease (angiofollicular lymph node hyperplasia), increased levels of serum vascular endothelial growth factor (VEGF), organomegaly, endocrinopathy, edema, typical skin changes, and papilledema. [1] Solitary plasmacytomas most frequently occur in the bone but can also be found in soft tissues (extramedullary plasmacytoma). [2] We report a case that showed a rare association of POEMS syndrome with a plasmacytoma of the clivus.
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