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  • Title: Maternal age and outcome of preterm infants at discharge from the neonatal intensive care unit.
    Author: Eventov-Friedman S, Zisk-Rony RY, Nosko S, Bar-Oz B.
    Journal: Int J Gynaecol Obstet; 2016 Feb; 132(2):196-9. PubMed ID: 26476582.
    Abstract:
    OBJECTIVE: To assess the effect of maternal age on preterm neonates' survival free from major morbidity at discharge from two neonatal intensive care units in Jerusalem, Israel. METHODS: A retrospective chart review of two hospitals from 2009-2010 was performed. Eligible neonates were born at less than 35 weeks of gestation and survived to discharge. Major morbidity included at least one of the following: chronic lung disease, at least grade 3 intraventricular hemorrhage, periventricular leukomalacia, at least stage 3 retinopathy of prematurity, at least stage 2 necrotizing enterocolitis, or sepsis. RESULTS: The analysis was performed on 380 neonates of 294 mothers. Mean maternal age was 30.5 years (range, 17-52), mean gestational age was 31.5 weeks (range, 24-34), and mean birth weight was 1705.5 g (range, 460-3150). Of the neonates, 90 (23.7%) had major morbidity, which was associated with lower mean gestational age (29.5 weeks vs 32.3 weeks, P<0.001), birth weight (1326.5g vs 1822.2g, P<0.001), and the need for resuscitation at birth (P<0.001) in comparison with neonates without major morbidity. A comparison of maternal age between the two outcome groups yielded a nonsignificant result. A logistic regression model revealed that maternal age does not contribute significantly to poor neonatal outcomes. CONCLUSION: Advanced maternal age was not associated with major morbidity of preterm neonates at discharge from the neonatal intensive care units.
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