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  • Title: [Long-term results following fibrinolytic treatment of deep venous thromboses in the area of the pelvis and leg].
    Author: Thiele C, Theiss W, Kurfürst-Seebauer R.
    Journal: Vasa; 1989; 18(1):48-55. PubMed ID: 2648692.
    Abstract:
    68 patients who underwent fibrinolytic treatment due to deep vein thrombosis of the lower extremity were followed-up after a median time interval of 6.3 years. Phlebography was carried out in all patients prior to and following fibrinolytic treatment. 28% of all patients showed complete patency and 38% partial patency. 34% showed no improvement. For the long term follow-up, physical examination, doppler-sonography, phlebodynamometry and vein occlusion plethysmography were assessed. The acute intervention, regarding treatment, turned out to be the crucial prognostic parameter. While late symptoms and clinical findings on the one hand and site, extent and age of thrombosis prior to fibrinolytic treatment on the other hand did not correlate with one another, symptoms and clinical findings did indeed correlate quite well with the outcome of fibrinolytic treatment. Postthrombotic syndrom was rare in cases with complete patency. In cases where patency was only partially or not at all achieved, postthrombotic syndrom was present to a higher degree the more central and the more extensive the remaining thrombosis was.
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