These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: New cytotoxic clerodane diterpenes from the leaves of Premna tomentosa.
    Author: Rekha K, Richa P, Hymavathy A, Suresh Babu K, Madhusudana Rao J, Neha R D, Amitava D.
    Journal: J Asian Nat Prod Res; 2016; 18(3):215-21. PubMed ID: 26488184.
    Abstract:
    Bio-activity directed investigation of hexane extract from the leaves of Premna tomentosa led to the isolation of three new clerodane diterpenes (1-3) along with four known compounds (4-7). The structures of new compounds were established using IR, MS, 1D, and 2D NMR techniques. The in vitro cytotoxicity of the crude hexane extract and the isolated compounds were evaluated against seven human cancer cell lines and results indicated that compounds 2 and 4 depicted significant cytotoxicity against hepatocellular carcinoma cell line.
    [Abstract] [Full Text] [Related] [New Search]