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  • Title: [DNA modification and carcinogenesis--early events caused by a heterocyclic aromatic amine, Glu-P-1].
    Author: Shudo K, Hashimoto Y.
    Journal: Gan To Kagaku Ryoho; 1989 Mar; 16(3 Pt 2):445-50. PubMed ID: 2650626.
    Abstract:
    Isolation, structure and activity of a mutagen, 2-amino-6-methyldipyrido [1, 2-a: 3', 2'-d] imidazole (Glu-P-1), were summarized. The metabolic activation, its specific reaction with DNA and biomimetic mutation of proto-ras oncogene were described.
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