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  • Title: Insulin and growth hormone secretion in a leukaemic girl with hypothalamic syndrome.
    Author: Schilirò G, Russo A, Sciotto A, Vigo R.
    Journal: Acta Paediatr Scand; 1977 Mar; 66(2):261-3. PubMed ID: 265133.
    Abstract:
    The authors report a girl with acute lymphoblastic leukaemia presenting hypothalamic syndrome characterized by meningeal leukaemia, hyperphagia and obesity. Insulin and growth hormone secretion, studied with arginine and insulin stimulation tests, showed a high peak of serum insulin and no response of growth hormone. Insulin and growth hormone responses to these tests reverted to normal after intrathecal methotrexate.
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