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  • Title: Data Analysis Strategies for Protein Modification Identification.
    Author: Fu Y.
    Journal: Methods Mol Biol; 2016; 1362():265-75. PubMed ID: 26519183.
    Abstract:
    Mass spectrometry-based proteomics provides a powerful tool for large-scale analysis of protein modifications. Statistical and computational analysis of mass spectrometry data is a key step in protein modification identification. This chapter presents common and advanced data analysis strategies for modification identification, including variable modification search, unrestrictive approaches for modification discovery, false discovery rate estimation and control methods, and tools for modification site localization.
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