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Title: The impact of purposeful sharing by HLA matching in the South Eastern Organ Procurement Foundation (SEOPF). Author: Pfaff WW, Sanfilippo F, Lucas BA, Vaughn WK. Journal: Transplant Proc; 1989 Feb; 21(1 Pt 2):1405-7. PubMed ID: 2652453. Abstract: A voluntary system was created to foster early sharing of well-matched organs between like-minded renal transplantation programs. In the two historic periods 1982-85 and 1985-86, sharing programs (Category I & II) and nonsharing programs (Category III) had similar graft survival. In the study period 1986-88, graft survival improved in Category I and II programs and was unchanged in Category III programs. Highly sensitized recipients in sharing programs had an incremental gain of 15.0%, patients receiving multiple grafts 12.6%. Grafts derived from local donors and transplants in less sensitized patients also were improved but for less obvious reasons. The implementation of this study was followed by a slight decrement in delayed graft function. It is our conclusion that early graft sharing can result in improved overall early graft survival.[Abstract] [Full Text] [Related] [New Search]