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  • Title: A polydopamine nanosphere based highly sensitive and selective aptamer cytosensor with enzyme amplification.
    Author: Fan D, Wu C, Wang K, Gu X, Liu Y, Wang E.
    Journal: Chem Commun (Camb); 2016 Jan 07; 52(2):406-9. PubMed ID: 26526224.
    Abstract:
    With CCRF-CEM as the model cell, a highly sensitive and selective cytosensor was developed by taking advantage of polydopamine nanospheres for the first time. The strategies of aptamer/membrane protein recognition and Exonuclease III assisted cycle amplification were used for improving selectivity and sensitivity. The detection of limit reached was as low as 15 cells per mL.
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