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  • Title: Diagnostic potential of endoscopic ultrasonography-elastography for gastric submucosal tumors: A pilot study.
    Author: Tsuji Y, Kusano C, Gotoda T, Itokawa F, Fukuzawa M, Sofuni A, Matsubayashi J, Nagao T, Itoi T, Moriyasu F.
    Journal: Dig Endosc; 2016 Mar; 28(2):173-8. PubMed ID: 26530730.
    Abstract:
    BACKGROUND AND AIM: Qualitative diagnosis for gastric submucosal tumors (SMT) is not easy. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in combination with EUS-elastography (EUS-EG) is reported useful for qualitatively diagnosing pancreatic tissues. We prospectively studied whether EUS-EG could be useful in qualitative diagnosis of gastric SMT. METHODS: We prospectively registered 25 consecutive patients with gastric SMT diagnosed by esophagogastroduodenoscopy and carried out qualitative evaluations using EUS-EG (May 2013 to March 2015) followed by histopathological diagnosis using EUS-FNA or endoscopic mucosal cutting biopsy. Elastic scores of gastric SMT were compared to the cytological diagnosis. RESULTS: Of 25 patients, 22 had a confirmed cytological diagnosis. Regarding the Giovannini elastic score, of three patients with aberrant pancreas, one was score 1 and two were score 2; of eight patients with leiomyoma, seven were score 2 and one was score 3. Both of two patients with schwannoma were score 4. Of nine patients with gastrointestinal stromal tumor, six were score 4 and three were score 5. Gastrointestinal stromal tumor (GIST) is harder than other types of gastric SMT, and our study's findings suggested the usefulness of EUS-EG, which can also assess tumor hardness of gastric SMT. CONCLUSION: EUS-EG might be helpful for the differential diagnosis of gastric SMT, especially to differentiate GIST from other SMT.
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